What is the difference between Joyalden, Rislane, and Purotide? A Complete Guide to Compare Hyaluronic Acid Brands
"I want to have hyaluronic acid, but the clinic said there are Giorgio Arden, Rislane, and Poronti, so what is the difference?" This is one of the most common questions I hear during consultations. All three brands are world-renowned hyaluronic acid manufacturers, but their design logic is different, and so are the areas they are suitable for. This article will help you understand the differences between the three brands in the most straightforward way, so that you will no longer be confused during your consultation.
What are hyaluronic acid injections? Why does the face need to be replenished?
Hyaluronic Acid (HA) originally exists in human tissues and is responsible for locking in moisture and maintaining skin fullness. When you are young, your face is full of tissue and has a three-dimensional silhouette; however, as you get older, your bones gradually absorb it, your fat pads shrink, and your skin loses support, so your face will start to "give out" - your apple muscles will sag, your tear troughs will deepen, and your wrinkles will become more pronounced.
The principle of hyaluronic acid injection is to inject the gel-like filler into the bottom layer of the skin to support the depression and restore the contour from inside. Because the ingredient itself is highly biocompatible and will be naturally absorbed by the body after metabolism, it is currently one of the most mainstream options for micropigmentation.
However, hyaluronic acid is not the same everywhere. Different brands have different gel hardness, softness, dispersion, and holding capacity, which is why doctors choose different brands and dosage forms for different parts of the body.
The Core Difference Between the Three Brands: It's Not Just About the Brand Name
Let's remember a core concept: the key difference between hyaluronic acid fillers is the "softness of the gel" and the "way it spreads in the tissue". To put it simply, when it is injected into the skin, does it hold up a point or does it blend evenly into the surrounding skin?
Juvéderm - long-lasting, homogeneous and versatile
Produced by the world-renowned pharmaceutical company Allergan (now part of AbbVie), the gel adopts the advanced Vycross technology, in which hyaluronic acid molecules of different lengths are intertwined to make the cross-linking structure more compact. The advantage is that the gel is highly resistant to degradation and remains stable in the human body for a relatively long period of time, up to 12 to 18 months for some dosage forms.
The Giorgio Arden line ranges from "extremely soft" to "extremely hard," from Volite, which is a delicate hydrating product, to Volux, which is designed for chin sculpting, and is carefully categorized for different parts of the body. Overall, Joyalden has been recognized for its balance between "visible contouring" and "natural, even transition".
Restylane - Strong support and more natural dynamic expression
Developed by Galderma, it has one of the longest histories of use and the largest clinical literature on the market. Rislane has two technology lines:
NASHA Technology (conventional dosage form): The gel is so hard that it will form small support points under the skin, like small pillars driven into the tissue. It is suitable for deep areas that need strong support, such as deep apple muscle reconstruction and chin contouring.
OBT Dynamic Optimization Technology: This is a relatively new technology, the gel can be stretched naturally with muscle movement, especially suitable for facial lines, lips and other areas of active expression, there will be no stiffness or unnatural bulge when smiling.
Another feature of Resilon is its "cumulative maintenance effect" - clinical tracking shows that by adding a small dose 18 months after the initial injection, the overall effect can be extended for a longer period of time, with subsequent additions gradually decreasing in dosage.
Belotero - the lightest, most suitable for light refining.
From Merz Aesthetics, Germany, using the unique CPM (Cohesive Multi-Density Matrix) technology. The most important feature of Paurité is its "high cohesion" - it does not form separate hard lumps after injection, but penetrates evenly into the small spaces of the dermis like a stream of water, and blends perfectly with the tissue.
This feature makes PUROTE particularly advantageous in "very thin skin areas", such as fine lines around the eyes and tear troughs. When used in these areas, there is a very low incidence of the "Tindall effect" (the blue shadowing of light refracted by hyaluronic acid in the shallow skin), resulting in a more natural and invisible look.
Compare the three brands: which part to choose?
| place | Juvéderm | Restylane | Belotero |
|---|---|---|---|
| Tear Trough / Around the Eye | Volite Small Molecule Hydration | Deep periosteal injections, physician evaluation required | ◆Soft / Balance preferred, good tissue integration, no Tilde's ear effect. |
| Apple Muscle / Couple's Palace | Voluma Macromolecular Deep Lifting | NASHA Lyft Strong Vertical Support | Intense / Volume Dose Support Reconstruction |
| stripe | Volift is both supportive and flexible. | ◆OBT Defyne dynamic extension, more natural smile | Balance Medium Deep Fill |
| lip | Volbella Soft Natural Lip Plumping | ◆OBT Kysse is designed for lips and adapts to speech movements. | Balance Enhanced Lip Line |
| Chin / Jawline | ◆Volux Extra Hard agent, strong contouring power. | Lyft Deep Skeletal Support | Intense / Volume auxiliary sculpture |
| Superficial Fine Lines / Hydration | Volite Deep Hydration | Vital improves skin texture | ◆Soft / Revive is the preferred choice for light refinishing. |
It's important to note that clinicians don't always use just one brand. In many cases, it's better to use one brand for deeper structures and another for lighter trims to achieve a balance of support and naturalness-which is why it's important to talk to your surgeon before surgery to understand your needs.
What is the price of Hyaluronic Acid in Taiwan?
In Taiwan, the market price range of the three major international brands is quite similar, with the overall price per c.c. range being about $4,000 per c.c.. NT$15,000 to NT$20,000The actual price varies depending on the clinic, the doctor, the injection site and the amount of injection, the following is the market reference range:
| branding | Reference price range (/c.c.) | Market Positioning |
|---|---|---|
| Juvéderm | About $16,000 - $20,000 | Complete dosage form, long-lasting and stable, and widely recognized for contour improvement. |
| Restylane | About $15,000 - $20,000 | Longest history, dynamic naturalness and long-lasting support |
| Belotero | Depends on the clinic's quote | Refinement of shallow layers, suitable for the eye area, blending sensation delicate |
The above figures are for reference only and the actual cost will depend on the amount and location of the injection and the individual's needs.
What should I pay attention to before and after the injection?
Pre-operative Note
One week before the injection, avoid taking aspirin, fish oil, vitamin E, ginkgo biloba, and other supplements or medications that may affect blood clotting to minimize the risk of bruising. If you have a history of severe allergies, are allergic to hyaluronic acid ingredients, or have had surgery on the same area within the last six months, please inform your doctor. Pregnant or breastfeeding women are advised to hold off on the procedure. Honestly informing your doctor of your medication history and previous injections will help your doctor choose the most appropriate brand and dosage form.
Post-Operative Attention
Apply ice packs moderately after injection to help minimize swelling and bruising. Avoid high-temperature environments, including saunas, soups, steam baths, and strenuous aerobic exercise for one week after injection. Avoid prolonged exposure to strong sunlight. If there is any unusual pain, change in skin color or persistent swelling at the injection site, please return to the doctor immediately.
Hyaluronic Acid Brand Comparison FAQ
Q1：Which of the three brands is better? There is no absolute "which one is better", the key lies in the needs of the application area. If you need strong support for the contour, you may choose a harder dose of Rislane or Joaden; for the tear troughs and the eye area, where the skin is thinner, the fusion of PUROTE is a priority for many doctors. The actual choice should be evaluated by the physician based on the individual's face shape, skin condition and improvement goals.
Q2: How long can hyaluronic acid last? Depending on the brand, dosage form and site of application, the large molecule deep dosage form can last about 12 to 18 months, while the small molecule shallow hydration form lasts about 9 to 12 months. Individuals' metabolic rate also affects the duration of maintenance, so it is recommended to discuss the follow-up program with your doctor.
Q3: Is hyaluronic acid injection safe? What are the side effects? Hyaluronic acid is highly biocompatible and can be naturally absorbed by the body after metabolism. Common post-operative reactions include slight redness, swelling and bruising, which usually subside within a few days. However, injection is still an invasive medical practice. It is recommended to choose a doctor with a professional background in plastic surgery or dermatology to perform the procedure to minimize the risk of inappropriate injections.
Q4：Which brand is suitable for the lines and tear troughs? For facial lines that involve frequent expression movements such as smiling and speaking, it is recommended to choose hyaluronic acid with dynamic extensibility, such as Rislane OBT series or Joyalden Volift. As the skin in the tear trough area is thin and densely populated with blood vessels, it is recommended to use Soft or Balance dosage form, which is soft and has good tissue fusion, in order to minimize the risk of the Tilde's ear effect (subcutaneous blue light).
Q5：Will my face become looser after the hyaluronic acid is metabolized? This is a common question. Generally speaking, after hyaluronic acid is metabolized, the condition of the face will return to its pre-injection base and will not age faster or become more flabby as a result of the injections. Maintaining good maintenance habits and sun protection will help slow down the rate of tissue loss.
Q6：Can hyaluronic acid be dissolved if I am not satisfied? Yes, hyaluronic acid fillers can be dissolved using Hyaluronidase, which is one of the advantages of hyaluronic acid over other fillers in terms of reversibility. It is recommended to return to the clinic and talk to your doctor if you have any concerns about your results, so that he or she can assess whether any adjustments are needed.
Q7: Can more than one area be injected at the same time? Theoretically, it is possible, but the actual site and dosage need to be evaluated by the surgeon according to the conditions of the individual's face, blood vessel distribution and tissue condition, and not everyone is suitable for treating multiple areas at one time. During the preoperative consultation, you can present your complete needs, and the surgeon will plan an appropriate treatment plan.
Quality Assurance for Hyaluronic Acid at Aerisin Medical Clinic
Hyaluronic acid injections may seem simple, but the choice of brand, dosage form, injection level and dosage all have a profound impact on the naturalness and maintenance of the final result. Our team of physicians is familiar with the clinical characteristics of the three major brands and their combined injection strategies, and can provide personalized treatment planning recommendations based on each patient's facial features, needs, and lifestyle.