Doublyx EVO Elastic Needle
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Doublyx EVO Elastic NeedleService Description
Doublyx EVO Elasticity Needle|Awakening the Original Elasticity

Doublyx EVO is a highly concentrated, non-cross-linked "Bio-stimulant" containing up to 40mg of medium molecular weight purified Hyaluronic Acid per injection. Unlike traditional filler hyaluronic acid, after injection into the dermis, the Elastin injections precisely bind to the CD44 receptor on the surface of fibroblasts, sending out the biological command of "active collagen synthesis", allowing the skin to spontaneously rebuild its youthful base from within. This is not a cover-up, but a real change from the inside out.
Prof. Dr. Roberto De Santis, Principal Investigator of the Italian National Research Council, states, "The goal of Doublyx EVO treatment is not volume filling, but rather the restoration of superficial skin function and reestablishment of Treat Quality."
What are Stretch Needles? Core Technology Explained

Activate CD44 "Youth Switch"
Doublyx EVO utilizes a unique 1200-1800 kDa medium molecular weight hyaluronic acid, a specific molecular weight that is the "exact key" to CD44, the receptor on the surface of fibroblasts in the dermis.
CD44 is the key sensor for deep skin regeneration, like a precise biological lock waiting for the right key to open. After the injection of the elastin needle, the combination of the two directly orders the cells to actively synthesize collagen and elastin to rebuild the supporting structure of the skin from the microenvironment, so that the skin can truly repair itself at the physiological level, rather than just filling in the external cover.
Extracellular matrix remodeling (ECM): improving skin texture from the ground up
Think of the ECM of the skin as the inner structure of a mattress:
- Collagen = spring skeleton: Provides strong support and thickness of the skin.
- Elastin = Memory Foam: Provides "resilience" and maintains firmness and flaccidity
- Hyaluronic Acid = Moisture Cotton: Fill in between structures to maintain cellular environment and moisturizing fullness.
As we age, we lose all three elements simultaneously, and our skin begins to sag and droop. After the injection of elasticity needle, while replenishing the deep water, it induces the cell factory to restart, actively repairing the three, and regaining the support and resilience of the young.
High purity and high safety
Using non-animal sources (Streptococcus equi bacterial fermentation), after two precipitation, dehydration and vacuum drying of the purification process, the protein and endotoxins are completely removed to achieve medical-grade purity. It has passed the European CE Class III top-level certification and ISO 13485 international medical material quality certification. It is highly biocompatible and can be safely metabolized by the human body naturally.
Three Core Benefits of Stretch Needle
1. Extremely high concentration formula Each 2mL bottle contains up to 40mg of Hyaluronic Acid (20mg/mL), which provides a strong moisturizing base and sufficient signal strength to ensure effective activation of fibroblasts for active repair.
2. Non-crosslinked structure・extremely natural The non-crosslinked linear structure is soft and spreads evenly in the dermis without forming knots or hard lumps, and has a natural look and feel after surgery, without "bunting" or a foreign feeling.
3. Swiss high purity process Non-animal source, through the European Union CE Class III and ISO 13485 dual certification, to meet the medical grade purity standards, safety is beyond doubt.
The Four Core Benefits of the Elastic Needle (4D Remodeling)

- Firmness & Restructuring: Stimulates the renewal of collagen and elastin to rebuild the skin's support from within, improving sagging and blurring of contours.
- Deep Hydration: Highly concentrated hyaluronic acid directly replenishes the dermal moisture reservoir, completely solving the problem of deep dehydration that cannot be penetrated by topical moisturizers.
- Repair & Rejuvenation: Repair superficial damage caused by sun exposure, aging or acne scars, and improve dullness and uneven skin texture.
- Barrier Protection (Protection): Rebuilds the skin's healthy protective barrier, allowing the absorption of subsequent moisturizers to be dramatically increased, maintaining a long-term moisturized and radiant state.
Clinical Data
Doublyx EVO was originally developed in Italy as part of a rigorous Multicenter Clinical Study with a 135-day longitudinal follow-up of subjects of all ages:
- Wrinkles are visibly smoothed: The wrinkle score, as assessed by the Modified Fitzpatrick Wrinkle Scale (MFWS), dropped significantly from 2-3 points (moderate/deep wrinkles) before treatment to 0.5-1.5 points (very shallow/light wrinkles) after treatment.
- Long-term maintenance: Until day 135 at the end of the study, the wrinkle improvement was maintained in all subjects, proving that the collagen renewal induced by the elastin injections is real and long-lasting.
- Physician Evaluation (GAIS): Over 95% subjects rated "Significantly Improved" or "Extremely Improved" in skin texture, moisturization and wrinkle depth.
- Patient self-assessment: More than 90% subjects were satisfied or very satisfied with the results.
- Recommendation: Subjects with more than 95% were willing to recommend this treatment to a friend.
4 BRP injections (Bio Revitalization Points)
Doublyx EVO utilizes the patented BRP injection method, which requires only 4 injection sites on each side of the face, with a precise injection of 0.25mL per site:
- Significantly reduces the number of needle insertions: Significantly reduces pain and discomfort, shortens operation time
- Reduce the risk of bruisingAnatomically designed to avoid major blood vessels and nerves.
- Wide coverage of center face: Although the points are simple, hyaluronic acid can still spread evenly and activate the bio-activation reaction in the mid-face area completely.
- Socialize after surgery: Almost no recovery period, suitable for people with busy life, afraid of pain or seeking for low recovery period.
Suitable Groups
- Aging Skin & Preventive Maintenance Groups: Fine lines, blurring of facial lines, lack of elasticity, who want to intervene before aging becomes visible.
- Dry skin and malnutrition group: Extremely dry, dull skin, external care products can not really penetrate to improve the need for deep hydration
- Scar Repair Community: those with shallow acne scars and uneven skin texture who wish to improve the evenness and refinement of their skin texture.
- The group that seeks a sense of nature: Those who don't want to have the foreign feeling of fillers, and seek to enhance the original skin texture, natural and not overly "plasticized" effect.
- Multi-site Demand Community: Suitable for superficial skin problems such as neck lines, hand lines, knee lines, acne scars, stretch marks, etc., in addition to the face.
- Electroacoustic Post-surgical Care CommunityFor those who have already had sonic and electrolysis and wish to optimize the superficial skin texture to achieve the "deep firming + superficial brightening" multiplier effect.
Comparison of Elastin, Hyaluronic Acid and Collagen Booster
| Doublyx EVO Elastic Needle | General Hyaluronic Acid | Collagen Booster | |
|---|---|---|---|
| core positioning | Bio-stimulation & Skin Repair | Volumetric Fillers & Contouring | Gradual growth and deep support |
| base | Medium molecular weight non-cross-linked hyaluronic acid | Large/Medium/Small Crosslinked Hyaluronic Acid | Micronized Powder + Carrier Gel |
| Principle of action | Activate CD44 to awaken fibroblasts. | Physical filler space | Foreign body reaction induces collagen proliferation |
| Post-operative experience | Natural hydration and elasticity enhancement | Immediate results, contouring | Progressive Abundance |
| Treatment Recommendations | 4 intensive sessions during the year, then 2-3 sessions per year for maintenance | Single, 6-12 month refill | 2-3 times at 4-6 week intervals. |

Precautions before treatment
- Not suitable for those who are allergic to hyaluronic acid or the ingredients of this product.
- Not recommended for pregnant women, breastfeeding women, or persons under 18 years of age.
- Persons undergoing immunosuppressive therapy or suffering from autoimmune diseases must be evaluated by a physician.
- Not recommended for those with infections, dermatitis, or open wounds at the treatment site.
- If you have injected other fillers into the treatment area, please inform your doctor beforehand.
- Please inform us in advance if you are taking anticoagulant drugs or health food such as fish oil or ginkgo.
Post-treatment care
- Slight redness and swelling at the injection site is normal and can be relieved by applying ice packs.
- Avoid hot environments (baths, steam baths, saunas) for a few days.
- Enhanced moisturizing and sun care
- Avoid excessive pressure or massage on the treated area for a short period of time.
- If redness, swelling, pain or other abnormal reactions persist, consult your physician immediately.
Doublyx EVO Elastic NeedleImage movie
Doublyx EVO Elastic NeedleEffects and Indications
effect
After the injection, many patients feel an immediate lifting and firming sensation, followed by the activation of fibroblasts, which begin to produce collagen, followed by a few weeks of increasingly noticeable skin refinement, radiance and elasticity.
Indications
- Firming & Lifting: Improve facial laxity, blurred jawline, double chin
- Flattening of lines: Frown lines, forehead lines, neck lines
- Improved skin texture: dullness, dryness, poor nutritional absorption, enlarged pores
- Scar Repair: shallow acne scars, uneven skin texture
- Body Parts: Fine lines on hands (chicken claw hands), knee lines, stretch marks
Doublyx EVO Elastic NeedleDescription of the treatment process
- Online Appointment/Consultation
- Physician assessment of skin condition and planning of individualized treatment programs
- Cleanse skin and apply anesthetic for 20-30 minutes.
- The surgeon administers a precise 4-BRP injection in about 20-30 minutes.
- Post-operative hygiene instructions indicate that mild localized redness and swelling is normal and usually resolves spontaneously within a few hours.
- Follow-up visit (4 sessions recommended for full course of treatment)
Doublyx EVO Elastic NeedleRecommended Treatments
Sonic/Electrolysis (The main effect is to lift the deep fascia, and the elastic needle focuses on shallow dermal hydration and skin optimization, which can be combined to achieve the 1+1>2 multiplier effect of "deep firming + shallow translucent", and is a highly recommended combination of maintenance programs.
Rejuran The elasticity injection is responsible for stimulating collagen renewal at the deeper level, while the hydration injection strengthens the epidermal moisturizing barrier, both of which work in tandem to achieve a full level of hydration and elasticity from the inside out.
Picosecond Laser / Shuttle Laser The combination of lasers to address epidermal pigmentation and pore problems, and elastic needles to improve the dermal structure, results in a "tight, bright, and flat" high-quality skin with a more comprehensive effect.
Doublyx EVO Elastic NeedleCase Photos

Doublyx EVO Elastic NeedleFrequently Asked Questions
Q1:What is the difference between Doublyx EVO Fillers and normal hyaluronic acid fillers?
The biggest difference lies in the purpose of treatment. Generally, hyaluronic acid is used to fill in the volume to support the hollows, while elastin is a "biostimulant" that uses medium molecular weight non-crosslinked hyaluronic acid to precisely activate the CD44 receptor, allowing the skin to produce collagen and elastin on its own, which rebuilds a healthy and firm skin texture from the inside rather than filling in and covering it up from the outside.
Q2: Why is it recommended to take 4 shots? Is it effective to take only 1 shot?
Manufacturer's recommendation: administer the second dose within 30 days of the first dose, and then every 3-4 months for a total of 4 doses per year. The intensive signaling keeps the dermis in a highly efficient state of repair. While a single treatment can be effective, the depth and durability of improvement is more pronounced with a full course of treatments.
Q3:Does the treatment hurt? How long is the recovery period?
The 4-point BRP injection method requires only 4 precise points on each side of the face, significantly reducing the number of injections. With the pre-operative anesthesia, most patients report minimal pain. After the procedure, there is only a slight transient redness and swelling, which usually resolves on its own in a few hours, and most patients can return to their normal life on the same day.
Q4: How long will the effect last?
According to a multi-center clinical study in Italy, the improvement of wrinkles continues to be significant on the 135th day (about 4.5 months) after the completion of the treatment. After completing the basic treatment, it is recommended to have 2-3 maintenance treatments per year to maintain the optimal condition.
Q5:Does it bun up? Can I feel it?
No. Elastin is a non-cross-linked linear structure with high diffusivity and mobility. After injection, it spreads naturally and evenly in the dermis and blends perfectly with the tissue, without gathering into hard lumps or knots. Its function is to "tighten the skin structure and enhance the skin texture", not to support the volume, so it looks and feels very natural.
Q6:Besides the face, what other parts of the body can be injected?
The range of application is quite wide. In addition to cheeks and cheekbones, neck lines, fine lines on the hands (chicken claw hands), skin lines on the knees, shallow acne scars, stretch marks, etc. are all suitable areas for application.
Q7:If I have already had the Sonic and Electrolysis, can I still have the Elastin Injection?
Very suitable! Sonic and electric wave mainly work on deep fascia lifting, and elastic needle focuses on shallow dermal hydration and skin quality optimization, the two can achieve "deep lifting + shallow brightening" multiplier effect, is highly recommended for complex maintenance program.
Q8: Are elastic injections safe? What are the certifications?
Safety is unquestionable. Developed in Switzerland and manufactured in Italy, it complies with the highest safety standards for medical devices in the European Union, obtains CE Class III certification, and the manufacturing plant is ISO 13485 certified. High purity hyaluronic acid from non-animal sources is highly biocompatible and can be safely metabolized by the human body.
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